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Atipamezole hydrochloride

CAS No. 104075-48-1

Atipamezole hydrochloride ( MPV-1248 hydrochloride;MPV1248 hydrochloride )

Catalog No. M10208 CAS No. 104075-48-1

Antipamezole (MPV-1248) is a potent, specific α2-adrenoceptor antagonist with Ki of 1.6 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Atipamezole hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Antipamezole (MPV-1248) is a potent, specific α2-adrenoceptor antagonist with Ki of 1.6 nM.
  • Description
    Antipamezole (MPV-1248) is a potent, specific α2-adrenoceptor antagonist with Ki of 1.6 nM; reverses the effects of the sedative dexmedetomidine and medetomidine as a veterinary drug.Alcoholism Phase 1 Discontinued
  • Synonyms
    MPV-1248 hydrochloride;MPV1248 hydrochloride
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    α2-adrenoceptor
  • Research Area
    Neurological Disease
  • Indication
    Alcoholism

Chemical Information

  • CAS Number
    104075-48-1
  • Formula Weight
    248.75
  • Molecular Formula
    C14H17ClN2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 47 mg/mL
  • SMILES
    CCC1(CC2=CC=CC=C2C1)C3=CN=CN3.Cl
  • Chemical Name
    1H-Imidazole, 5-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-, hydrochloride (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pertovaara A, et al. CNS Drug Rev. 2005 Autumn;11(3):273-88.
2. Scheinin H, et al. Eur J Pharmacol. 1988 Jun 22;151(1):35-42.
3. Scheinin H, et al. Eur J Pharmacol. 1986 Sep 23;129(1-2):113-21.
4. Karhuvaara S, et al. Br J Clin Pharmacol. 1990 Jul;30(1):97-106.
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